Well, the distributor would be off, but don't believe it would be 180°, you have a 6 cyl 4 cycle engine. My mind is tired and don't really want to figure all the variables. I find it easier to just ensure TDC compression. You can do this by pulling #1 plug, put something like a cotton ball in the hole and turn the crankshaft by hand while watching the ball. When it pops up, you know you are on the compression stroke. Then you can use a long screwdriver or other rod that is long enough to reach the piston top. Watching the rod, turn the crankshaft until the rod hits it's highest point. That will have you at TDC compression. Then you can install the distributor with the rotor arm pointing to #1 tower on the cap.
I find it easier to mark the base of the distributor where #1 is so aligning that rotor is easier. Set the distributor into place and see how far the rotor turns. Then pull the distributor back out, turn the rotor the same distance the opposite side of the mark. Then when you put the distributor back in, the rotor should be lined up with your mark.
That should get you pretty much at 0° TDC. You should be able to get the engine to start and finish setting the base timing.